Skip Navigation



MBE Advance Access published online on April 17, 2007
Molecular Biology and Evolution, doi:10.1093/molbev/msm074
This Article
Right arrow Advance Access manuscript (PDF) Freely available
Right arrow Supplementary Material
Right arrow All Versions of this Article:
24/7/1528    most recent
msm074v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Nash, E. A.
Right arrow Articles by Nisbet, R. E. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nash, E. A.
Right arrow Articles by Nisbet, R. E. R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2007. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Research Article

Organisation of the Mitochondrial Genome in the Dinoflagellate Amphidinium carterae

Edmund A. Nash1, Adrian C. Barbrook1, Rachel K. Edwards-Stuart2, Kaj Bernhardt1, Christopher J. Howe1 and R. Ellen R. Nisbet1,3

1 Department of Biochemistry, University of Cambridge, Cambridge, UK
2 Current address: Division of Food Sciences, University of Nottingham, Loughborough, UK

3 To whom correspondence should be addressed: Department of Biochemistry, University of Cambridge, Cambridge, UK. Tel +44 (0)1223 333687, Fax +44 (0)1223 333345, email rern2{at}mole.bio.cam.ac.uk

Received for publication February 7, 2007. Revision received March 26, 2007. Accepted for publication April 4, 2007.

We have characterized the mitochondrial genome of the dinoflagellate Amphidinium carterae. It contains just three identifiable protein-coding genes: cox1, cox3 and cob. No evidence for rRNA or tRNA genes was found. EST sequences for the three genes suggest that RNA editing occurs, in two cases removing an in-frame stop codon. Two of the transcripts (cob and cox1) lack a stop codon at the end of the gene. The genome contains a large amount of non-coding DNA including many fragmented copies of all three genes and large numbers of inverted repeats. The genome, which contains about 70% AT, has undergone extensive recombination, possibly due to the inverted repeats. The highly reduced mitochondrial gene content supports the relationship of the dinoflagellates and apicomplexa as sister groups.

Key Words: alveolate • Amphidinium operculatum • Amphidinium carterae • dinoflagellate • mitochondrion


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Exp BotHome page
C. J. Howe, R. E. R. Nisbet, and A. C. Barbrook
The remarkable chloroplast genome of dinoflagellates
J. Exp. Bot., March 3, 2008; (2008) erm292v1.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
D. R. Smith and R. W. Lee
Mitochondrial Genome of the Colorless Green Alga Polytomella capuana: A Linear Molecule with an Unprecedented GC Content
Mol. Biol. Evol., March 1, 2008; 25(3): 487 - 496.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.