Skip Navigation



MBE Advance Access published online on September 8, 2005
Molecular Biology and Evolution, doi:10.1093/molbev/msj010
This Article
Right arrow Advance Access manuscript (PDF) Freely available
Right arrow All Versions of this Article:
23/1/86    most recent
msj010v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Allen, M. J.
Right arrow Articles by Wilson, W. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Allen, M. J.
Right arrow Articles by Wilson, W. H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oupjournals.org
Accepted August 30, 2005

Research Article

Evolutionary History of the Coccolithoviridae

Michael J. Allen 1, Declan C. Schroeder 2, Matthew T.G. Holden 3, and William H. Wilson 1*

1 Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, PL1 3DH, UK
2 Marine Biological Association, Citadel Hill, Plymouth, PL1 2PB, UK
3 The Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK

* To whom correspondence should be addressed.
William H. Wilson, E-mail: whw{at}pml.ac.uk


  Abstract

We recently determined the genome sequence of the Coccolithoviridae strain EhV-86, a giant dsDNA algal virus from the family Phycodnaviridae that infects the marine coccolithophorid Emiliania huxleyi. Here, we determine the phylogenetic relationship between EhV-86 and other large dsDNA viruses. Twenty-five core genes common to nuclear-cytoplasmic large DNA virus (NCLDV) genomes were identified in the EhV-86 genome, sequence from eight of these genes were used to create a phylogenetic tree in which EhV-86 was placed firmly with the two other members of the Phycodnaviridae. We have also identified a 100kb region of the EhV-86 genome which appears to have transferred into this genome from an unknown source. Furthermore, the presence of six RNA polymerase subunits (unique among the Phycodnaviridae) suggests both a unique evolutionary history and a unique life style for this intriguing virus.

Keywords: Phycodnaviridae; Coccolithoviridae; virus; evolution; NCLDV; Emiliania huxleyi.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Appl. Environ. Microbiol.Home page
J. B. Larsen, A. Larsen, G. Bratbak, and R.-A. Sandaa
Phylogenetic Analysis of Members of the Phycodnaviridae Virus Family, Using Amplified Fragments of the Major Capsid Protein Gene
Appl. Envir. Microbiol., May 15, 2008; 74(10): 3048 - 3057.
[Abstract] [Full Text] [PDF]

Home page
 Brief Funct Genomic ProteomicHome page
M. J. Allen and W. H. Wilson
The coccolithovirus microarray: an array of uses
Brief Funct Genomic Proteomic, December 1, 2006; 5(4): 273 - 279.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
M. J. Allen, T. Forster, D. C. Schroeder, M. Hall, D. Roy, P. Ghazal, and W. H. Wilson
Locus-specific gene expression pattern suggests a unique propagation strategy for a giant algal virus.
J. Virol., August 1, 2006; 80(15): 7699 - 7705.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.