MBE Advance Access published online on October 6, 2004
Molecular Biology and Evolution, doi:10.1093/molbev/msi003
Molecular Biology and Evolution © Society for Molecular Biology and Evolution 2004; all rights reserved
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 School of Biosciences, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
* To whom correspondence should be addressed. E-mail: d.filatov{at}bham.ac.uk.
Dioecious white campion Silene latifolia has sex chromosomal sex determination, with homogametic (XX) females and heterogametic (XY) males. This species has become a popular in studies of sex chromosome evolution. However, the lack of genes isolated from the X and Y chromosomes of this species is a major obstacle for such studies. Here I report the isolation of a new sex-linked gene, Slss, with strong homology to spermidine synthase genes of other species. The new gene has homologous intact copies on the X and Y chromosomes (SlssX, and SlssY, respectively). Synonymous divergence between the SlssX and SlssY genes is 4.7%, while non-synonymous divergence is 1.4%. Isolation of a homologous gene from nondioecious S. vulgaris provided a root to the gene tree and allowed the estimation of the silent and replacement substitution rates along the SlssX and SlssY lineages. Interestingly, the Y-linked gene has higher synonymous and non-synonymous substitution rates. The elevated synonymous rate in the SlssY gene, compared to SlssX confirms our previous suggestion that the S. latifolia Y chromosome has a higher mutation rate, compared to the X chromosome. When differences in silent substitution rate are taken into account, the Y-linked gene still demonstrates significantly faster accumulation of non-synonymous substitutions, which is consistent with the theoretical prediction of relaxed purifying selection in Y-linked genes, leading to the accumulation of non-synonymous substitutions and genetic degeneration of the Y-linked genes.
Research Article
Substitution Rates in a New Silene Latifolia Sex-Linked Gene, SlssX/Y
Abstract 
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  E. C. Howell, S. J. Armstrong, and D. A. Filatov Evolution of Neo-Sex Chromosomes in Silene diclinis Genetics, August 1, 2009; 182(4): 1109 - 1115. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Kazama, M. T. Fujiwara, A. Koizumi, K. Nishihara, R. Nishiyama, E. Kifune, T. Abe, and S. Kawano A SUPERMAN-like Gene is Exclusively Expressed in Female Flowers of the Dioecious Plant Silene latifolia Plant Cell Physiol., June 1, 2009; 50(6): 1127 - 1141. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. A. Filatov, E. C. Howell, C. Groutides, and S. J. Armstrong Recent Spread of a Retrotransposon in the Silene latifolia Genome, Apart From the Y Chromosome Genetics, February 1, 2009; 181(2): 811 - 817. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Bergero, A. Forrest, and D. Charlesworth Active Miniature Transposons From a Plant Genome and Its Nonrecombining Y Chromosome Genetics, February 1, 2008; 178(2): 1085 - 1092. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Koizumi, Y. Amanai, K. Ishii, K. Nishihara, Y. Kazama, W. Uchida, and S. Kawano Floral Development of an Asexual and Female-Like Mutant Carrying Two Deletions in Gynoecium-Suppressing and Stamen-Promoting Functional Regions on the Y Chromosome of the Dioecious Plant Silene latifolia Plant Cell Physiol., October 1, 2007; 48(10): 1450 - 1461. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Zluvova, S. Georgiev, B. Janousek, D. Charlesworth, B. Vyskot, and I. Negrutiu Early Events in the Evolution of the Silene latifolia Y Chromosome: Male Specialization and Recombination Arrest Genetics, September 1, 2007; 177(1): 375 - 386. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Bergero, A. Forrest, E. Kamau, and D. Charlesworth Evolutionary Strata on the X Chromosomes of the Dioecious Plant Silene latifolia: Evidence From New Sex-Linked Genes Genetics, April 1, 2007; 175(4): 1945 - 1954. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Ming, J. Wang, P. H. Moore, and A. H. Paterson Sex chromosomes in flowering plants Am. J. Botany, February 1, 2007; 94(2): 141 - 150. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Bachtrog Sex chromosome evolution: Molecular aspects of Y-chromosome degeneration in Drosophila Genome Res., October 1, 2005; 15(10): 1393 - 1401. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Zluvova, B. Janousek, I. Negrutiu, and B. Vyskot Comparison of the X and Y Chromosome Organization in Silene latifolia Genetics, July 1, 2005; 170(3): 1431 - 1434. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. A. Filatov Evolutionary History of Silene latifolia Sex Chromosomes Revealed by Genetic Mapping of Four Genes Genetics, June 1, 2005; 170(2): 975 - 979. [Abstract] [Full Text] [PDF]
|
|