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MBE Advance Access published online on May 30, 2003
Molecular Biology and Evolution, doi:10.1093/molbev/msg148
Molecular Biology and Evolution © Society for Molecular Biology and Evolution 2003; all rights reserved
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Accepted April 4, 2003
© 2003 Society for Molecular Biology and Evolution

Original Articles

Non-Neutral Admixture of Immigrant Genotypes in African D. melanogaster Populations from Zimbabwe

Maximilian Kauer 1, Daniel Dieringer 1, Christian Schlötterer 1*

1 Institut für Tierzucht und Genetik, Josef-Baumann Gasse 1, 1210 Wien

* To whom correspondence should be addressed. E-mail: Christian.Schloetterer{at}vu-wien.ac.at.


  Abstract

D. melanogaster originated in Africa and colonized the rest of the world only recently (approx. 10-15,000 years ago). Using 151 microsatellite loci we investigated patterns of geneflow between African D. melanogaster populations representing presumptive ancestral variation and recently colonized European populations. While we detected almost no evidence for alleles of non-African ancestry in a rural D. melanogaster population from Zimbabwe, an urban population from Zimbabwe showed evidence for admixture. Interestingly, the degree of admixture differed among chromosomes. X-chromosomes of both rural and urban populations showed almost no non-African ancestry, but the third chromosome in the urban population showed up to 70% of non-African alleles. When chromosomes were broken into contingent microsatellite blocks even higher estimates of admixture and significant heterogeneity in admixture was observed among these blocks. The discrepancy between the X-chromosome and chromosome three is not consistent with a neutral admixture hypothesis. The higher number of European alleles on the third chromosome could be due to stronger selection against foreign alleles on the X-chromosome or to more introgression of (beneficial) alleles on the third chromosome.

Key Words: Drosophila melanogaster, geneflow, selection, habitat adaptation, antagonistic pleiotropy


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