Skip Navigation


MBE Advance Access originally published online on March 31, 2006
Molecular Biology and Evolution 2006 23(6):1293-1303; doi:10.1093/molbev/msk016
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Supplementary Material
Right arrow All Versions of this Article:
23/6/1293    most recent
msk016v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (7)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by De Bodt, S.
Right arrow Articles by Van de Peer, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by De Bodt, S.
Right arrow Articles by Van de Peer, Y.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Research Article

Promoter Analysis of MADS-Box Genes in Eudicots Through Phylogenetic Footprinting

Stefanie De Bodt*, Guenter Theissen{dagger} and Yves Van de Peer*

* Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology, Ghent University, Ghent, Belgium; and {dagger} Department of Genetics, Friedrich-Schiller-University, Jena, Germany

E-mail: yves.vandepeer{at}psb.ugent.be.

The MIKC MADS-box gene family has been shaped by extensive gene duplications giving rise to subfamilies of genes with distinct functions and expression patterns. However, within these subfamilies the functional assignment is not that clear-cut, and considerable functional redundancy exists. One way to investigate the diversity in regulation present in these subfamilies is promoter sequence analysis. With the advent of genome sequencing projects, we are now able to exert a comparative analysis of Arabidopsis and poplar promoters of MADS-box genes belonging to the same subfamily. Based on the principle of phylogenetic footprinting, sequences conserved between the promoters of homologous genes are thought to be functional. Here, we have investigated the evolution of MADS-box genes at the promoter level and show that many genes have diverged in their regulatory sequences after duplication and/or speciation. Furthermore, using phylogenetic footprinting, a distinction can be made between redundancy, neo/nonfunctionalization, and subfunctionalization.

Key Words: phylogenetic footprinting • MADS-box genes • eudicots • evolution • promoter


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Plant CellHome page
M. Freeling, L. Rapaka, E. Lyons, B. Pedersen, and B. C. Thomas
G-Boxes, Bigfoot Genes, and Environmental Response: Characterization of Intragenomic Conserved Noncoding Sequences in Arabidopsis
PLANT CELL, May 1, 2007; 19(5): 1441 - 1457.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
L. C. Hileman, J. F. Sundstrom, A. Litt, M. Chen, T. Shumba, and V. F. Irish
Molecular and Phylogenetic Analyses of the MADS-Box Gene Family in Tomato
Mol. Biol. Evol., November 1, 2006; 23(11): 2245 - 2258.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.