Skip Navigation


MBE Advance Access originally published online on December 20, 2005
Molecular Biology and Evolution 2006 23(5):887-892; doi:10.1093/molbev/msj083
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
23/5/887    most recent
msj083v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (20)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Crow, K. D.
Right arrow Articles by Wagner, G. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Crow, K. D.
Right arrow Articles by Wagner, G. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Proceedings of the SMBE Tri-National Young Investigators' Workshop 2005

What Is the Role of Genome Duplication in the Evolution of Complexity and Diversity?

Karen D. Crow and Günter P. Wagner

Department of Ecology and Evolutionary Biology, Yale University

E-mail: karen.crow{at}yale.edu.

Gene and genome duplications provide a source of genetic material for mutation, drift, and selection to act upon, making new evolutionary opportunities possible. As a result, many have argued that genome duplication is a dominant factor in the evolution of complexity and diversity. However, a clear correlation between a genome duplication event and increased complexity and diversity is not apparent, and there are inconsistencies in the patterns of diversity invoked to support this claim. Interestingly, several estimates of genome duplication events in vertebrates are preceded by multiple extinct lineages, resulting in preduplication gaps in extant taxa. Here we argue that gen(om)e duplication could contribute to reduced risk of extinction via functional redundancy, mutational robustness, increased rates of evolution, and adaptation. The timeline for these processes to unfold would not predict immediate increases in species diversity after the duplication event. Rather, reduced probabilities of extinction would predict a latent period between a genome duplication and its effect on species diversity or complexity. In this paper, we will develop the idea that genome duplication could contribute to species diversity through reduced probability of extinction.

Key Words: genome duplication • extinction


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Genome ResHome page
K. S. Kassahn, V. T. Dang, S. J. Wilkins, A. C. Perkins, and M. A. Ragan
Evolution of gene function and regulatory control after whole-genome duplication: Comparative analyses in vertebrates
Genome Res., August 1, 2009; 19(8): 1404 - 1418.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. A. Fawcett, S. Maere, and Y. Van de Peer
From the Cover: Plants with double genomes might have had a better chance to survive the Cretaceous-Tertiary extinction event
PNAS, April 7, 2009; 106(14): 5737 - 5742.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. GenomicsHome page
H. Evans, T. De Tomaso, M. Quail, J. Rogers, A. Y. Gracey, A. R. Cossins, and M. Berenbrink
Ancient and modern duplication events and the evolution of stearoyl-CoA desaturases in teleost fishes
Physiol Genomics, September 17, 2008; 35(1): 18 - 29.
[Abstract] [Full Text] [PDF]

Home page
 Syst BiolHome page
C. Li, G. Lu, and G. Orti
Optimal Data Partitioning and a Test Case for Ray-Finned Fishes (Actinopterygii) Based on Ten Nuclear Loci
Syst Biol, August 1, 2008; 57(4): 519 - 539.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
D. L. Howarth, S. H. W. Law, B. Barnes, J. M. Hall, D. E. Hinton, L. Moore, J. M. Maglich, J. T. Moore, and S. W. Kullman
Paralogous Vitamin D Receptors in Teleosts: Transition of Nuclear Receptor Function
Endocrinology, May 1, 2008; 149(5): 2411 - 2422.
[Abstract] [Full Text] [PDF]

Home page
 Proc R Soc BHome page
I. A Hurley, R. L. Mueller, K. A Dunn, E. J Schmidt, M. Friedman, R. K Ho, V. E Prince, Z. Yang, M. G Thomas, and M. I Coates
A new time-scale for ray-finned fish evolution
Proc R Soc B, February 22, 2007; 274(1609): 489 - 498.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.