Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Supplementary material
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (32)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Johanson, U.
Right arrow Articles by Gustavsson, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Johanson, U.
Right arrow Articles by Gustavsson, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution 19:456-461 (2002)
© 2002 Society for Molecular Biology and Evolution

A New Subfamily of Major Intrinsic Proteins in Plants

Urban Johanson and Sofia Gustavsson

Department of Plant Biochemistry, Lund University, Sweden

The major intrinsic proteins (MIPs) form a large protein family of ancient origin and are found in bacteria, fungi, animals, and plants. MIPs act as channels in membranes to facilitate passive transport across the membrane. Some MIPs allow small polar molecules like glycerol or urea to pass through the membrane. However, the majority of MIPs are thought to be aquaporins (AQPs), i.e., they are specific for water transport. Plant MIPs can be subdivided into the plasma membrane intrinsic protein, tonoplast intrinsic protein, and NOD26-like intrinsic protein subfamilies. By database mining and phylogenetic analyses, we have identified a new subfamily in plants, the Small basic Intrinsic Proteins (SIPs). Comparisons of sequences from the new subfamily with conserved amino acid residues in other MIPs reveal characteristic features of SIPs. Possible functional consequences of these features are discussed in relation to the recently solved structures of AQP1 and GlpF. We suggest that substitutions at conserved and structurally important positions imply a different substrate specificity for the new subfamily.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
S. Sundaram, B. Rathinasabapathi, L. Q. Ma, and B. P. Rosen
An Arsenate-activated Glutaredoxin from the Arsenic Hyperaccumulator Fern Pteris vittata L. Regulates Intracellular Arsenite
J. Biol. Chem., March 7, 2008; 283(10): 6095 - 6101.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
Y. Morishita, T. Matsuzaki, M. Hara-chikuma, A. Andoo, M. Shimono, A. Matsuki, K. Kobayashi, M. Ikeda, T. Yamamoto, A. Verkman, et al.
Disruption of Aquaporin-11 Produces Polycystic Kidneys following Vacuolization of the Proximal Tubule
Mol. Cell. Biol., September 1, 2005; 25(17): 7770 - 7779.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. Gustavsson, A.-S. Lebrun, K. Norden, F. Chaumont, and U. Johanson
A Novel Plant Major Intrinsic Protein in Physcomitrella patens Most Similar to Bacterial Glycerol Channels
Plant Physiology, September 1, 2005; 139(1): 287 - 295.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
M. I. Anderca, S. Suga, T. Furuichi, K. Shimogawara, M. Maeshima, and S. Muto
Functional Identification of the Glycerol Transport Activity of Chlamydomonas reinhardtii CrMIP1
Plant Cell Physiol., September 15, 2004; 45(9): 1313 - 1319.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
S. Suga and M. Maeshima
Water Channel Activity of Radish Plasma Membrane Aquaporins Heterologously Expressed in Yeast and Their Modification by Site-Directed Mutagenesis
Plant Cell Physiol., July 15, 2004; 45(7): 823 - 830.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
I. S. Wallace and D. M. Roberts
Homology Modeling of Representative Subfamilies of Arabidopsis Major Intrinsic Proteins. Classification Based on the Aromatic/Arginine Selectivity Filter
Plant Physiology, June 1, 2004; 135(2): 1059 - 1068.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.