Molecular Biology and Evolution 19:1816-1819 (2002)
© 2002 Society for Molecular Biology and Evolution
A Test for Faster X Evolution in Drosophila
*Department of Biology, University of Rochester, Rochester;
Department of Biology, University of California, Riverside
| The first 150 words of the full text of this article appear below. |
Charlesworth, Coyne, and Barton (1987)
showed that, under certain conditions, loci on the X chromosome are expected to have higher rates of adaptive evolution than those on the autosomes. In particular, if the average beneficial mutation is both new (i.e., not a previously deleterious allele segregating at mutation-selection balance; see Orr and Betancourt 2001
) and at least partially recessive (mean h < 0.5), X-linked loci will evolve faster (Charlesworth, Coyne, and Barton 1987
). (This calculation assumes that the distribution of selection coefficients does not systematically differ between X-linked and autosomal loci, as seems reasonable.) Although X-linked loci, having smaller population sizes than do autosomal loci, experience fewer beneficial mutations per generation, a greater fraction of these mutations is fixed by hemizygous selection in the XY sex (we assume hereafter that males are the XY sex). When h = 0.5, the two forces cancel each other, and X-linked and
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  N. D. Singh, P. F. Arndt, A. G. Clark, and C. F. Aquadro Strong Evidence for Lineage and Sequence Specificity of Substitution Rates and Patterns in Drosophila Mol. Biol. Evol., July 1, 2009; 26(7): 1591 - 1605. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. L. Bauer DuMont, N. D. Singh, M. H. Wright, and C. F. Aquadro Locus-Specific Decoupling of Base Composition Evolution at Synonymous Sites and Introns along the Drosophila melanogaster and Drosophila sechellia Lineages Gen Biol Evol, June 22, 2009; 2009(0): 67 - 74. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Ellegren Genomic evidence for a large-Z effect Proc R Soc B, January 22, 2009; 276(1655): 361 - 366. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. H. Takahashi, K. Tanaka, M. Itoh, and T. Takano-Shimizu Reduced X-Linked Rare Polymorphism in Males in Comparison to Females of Drosophila melanogaster J. Hered., January 1, 2009; 100(1): 97 - 105. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. F. Baines, S. A. Sawyer, D. L. Hartl, and J. Parsch Effects of X-Linkage and Sex-Biased Gene Expression on the Rate of Adaptive Protein Evolution in Drosophila Mol. Biol. Evol., August 1, 2008; 25(8): 1639 - 1650. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Bachtrog Evidence for Male-Driven Evolution in Drosophila Mol. Biol. Evol., April 1, 2008; 25(4): 617 - 619. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. D. Singh, A. M. Larracuente, and A. G. Clark Contrasting the Efficacy of Selection on the X and Autosomes in Drosophila Mol. Biol. Evol., February 1, 2008; 25(2): 454 - 467. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Connallon Adaptive Protein Evolution of X-linked and Autosomal Genes in Drosophila: Implications for Faster-X Hypotheses Mol. Biol. Evol., November 1, 2007; 24(11): 2566 - 2572. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Hutter, H. Li, S. Beisswanger, D. De Lorenzo, and W. Stephan Distinctly Different Sex Ratios in African and European Populations of Drosophila melanogaster Inferred From Chromosomewide Single Nucleotide Polymorphism Data Genetics, September 1, 2007; 177(1): 469 - 480. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. E. Mank, E. Axelsson, and H. Ellegren Fast-X on the Z: Rapid evolution of sex-linked genes in birds Genome Res., May 1, 2007; 17(5): 618 - 624. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. W. Hahn Accurate Inference and Estimation in Population Genomics Mol. Biol. Evol., May 1, 2006; 23(5): 911 - 918. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Thornton, D. Bachtrog, and P. Andolfatto X chromosomes and autosomes evolve at similar rates in Drosophila: No evidence for faster-X protein evolution Genome Res., April 1, 2006; 16(4): 498 - 504. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Tang and C.-I Wu A New Method for Estimating Nonsynonymous Substitutions and Its Applications to Detecting Positive Selection Mol. Biol. Evol., February 1, 2006; 23(2): 372 - 379. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Borge, M. T. Webster, G. Andersson, and G.-P. Saetre Contrasting Patterns of Polymorphism and Divergence on the Z Chromosome and Autosomes in Two Ficedula Flycatcher Species Genetics, December 1, 2005; 171(4): 1861 - 1873. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Mueller, K. R. Ram, L. A. McGraw, M. C. Bloch Qazi, E. D. Siggia, A. G. Clark, C. F. Aquadro, and M. F. Wolfner Cross-Species Comparison of Drosophila Male Accessory Gland Protein Genes Genetics, September 1, 2005; 171(1): 131 - 143. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. D. Singh, J. C. Davis, and D. A. Petrov X-Linked Genes Evolve Higher Codon Bias in Drosophila and Caenorhabditis Genetics, September 1, 2005; 171(1): 145 - 155. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Lu and C.-I Wu Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee PNAS, March 15, 2005; 102(11): 4063 - 4067. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Cutter and S. Ward Sexual and Temporal Dynamics of Molecular Evolution in C. elegans Development Mol. Biol. Evol., January 1, 2005; 22(1): 178 - 188. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Betancourt, Y. Kim, and H. A. Orr A Pseudohitchhiking Model of X vs. Autosomal Diversity Genetics, December 1, 2004; 168(4): 2261 - 2269. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Zhang, T. M. Hambuch, and J. Parsch Molecular Evolution of Sex-Biased Genes in Drosophila Mol. Biol. Evol., November 1, 2004; 21(11): 2130 - 2139. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Schofl and C. Schlotterer Patterns of Microsatellite Variability Among X Chromosomes and Autosomes Indicate a High Frequency of Beneficial Mutations in Non-African D. simulans Mol. Biol. Evol., July 1, 2004; 21(7): 1384 - 1390. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. S. Willett and R. S. Burton Evolution of Interacting Proteins in the Mitochondrial Electron Transport System in a Marine Copepod Mol. Biol. Evol., March 1, 2004; 21(3): 443 - 453. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. A. Sheldahl, D. M. Weinreich, and D. M. Rand Recombination, Dominance and Selection on Amino Acid Polymorphism in the Drosophila Genome: Contrasting Patterns on the X and Fourth Chromosomes Genetics, November 1, 2003; 165(3): 1195 - 1208. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. G. Torgerson and R. S. Singh Sex-Linked Mammalian Sperm Proteins Evolve Faster Than Autosomal Ones Mol. Biol. Evol., October 1, 2003; 20(10): 1705 - 1709. [Abstract] [Full Text]
|
|
|
|
|
|
Y. Tao, S. Chen, D. L. Hartl, and C. C. Laurie Genetic Dissection of Hybrid Incompatibilities Between Drosophila simulans and D. mauritiana. I. Differential Accumulation of Hybrid Male Sterility Effects on the X and Autosomes Genetics, August 1, 2003; 164(4): 1383 - 1397. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Maside, C. Bartolome, and B. Charlesworth Inferences on the Evolutionary History of the S-Element Family of Drosophila melanogaster Mol. Biol. Evol., August 1, 2003; 20(8): 1183 - 1187. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Michalak and M. A. F. Noor Genome-Wide Patterns of Expression in Drosophila Pure Species and Hybrid Males Mol. Biol. Evol., July 1, 2003; 20(7): 1070 - 1076. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. C. Presgraves A Fine-Scale Genetic Analysis of Hybrid Incompatibilities in Drosophila Genetics, March 1, 2003; 163(3): 955 - 972. [Abstract] [Full Text] [PDF]
|
|