Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (18)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Culver, M.
Right arrow Articles by O'Brien, S. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Culver, M.
Right arrow Articles by O'Brien, S. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution 18:1151-1156 (2001)
© 2001 Society for Molecular Biology and Evolution

LETTER

Patterns of Size Homoplasy at 10 Microsatellite Loci in Pumas (Puma concolor)

Melanie Culver, Marilyn A. Menotti-Raymond and Stephen J. O'Brien

Laboratory of Genomic Diversity, National Cancer Institute–Frederick, Frederick, Maryland

Microsatellites, repetitive simple sequences of 1–6 nt in length, are abundant in eukaryotic genomes (Weber 1990aCitation ). Because of extensive variability in the number of repeat units for any one locus among members of a population, microsatellite loci exhibit high polymorphism. Microsatellite variation has become a useful class of genetic markers in population assessment for numerous species for questions of genetic identification, parentage, kinship, and population variability assessment (Jarne and Lagoda 1996Citation ; Goldstein and Pollock 1997Citation ).

The high level of polymorphism at microsatellite loci is believed to result from slipped-strand mispairing during DNA replication (Levinson and Gutman 1987Citation ; Weber 1990bCitation ; Weber and Wong 1993Citation ; Krugylak et al. 1998Citation ), most commonly causing the gain or loss of one or more repeat units. This mutation mechanism would be expected to generate allelic homoplasy, i.e., comigrating allele size fragments which are not identical by descent . . . [Full Text of this Article]

Acknowledgements

Footnotes

literature cited


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J MOLLUS STUDHome page
J. W. Jones, R. J. Neves, S. A. Ahlstedt, and E. M. Hallerman
A holistic approach to taxonomic evaluation of two closely related endangered freshwater mussel species, the oyster mussel Epioblasma capsaeformis and tan riffleshell Epioblasma florentina walkeri (Bivalvia: Unionidae)
J. Mollus. Stud., August 1, 2006; 72(3): 267 - 283.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
J. R. Dettman and J. W. Taylor
Mutation and Evolution of Microsatellite Loci in Neurospora
Genetics, November 1, 2004; 168(3): 1231 - 1248.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
S. M. Blankenship, B. May, and D. Hedgecock
Evolution of a Perfect Simple Sequence Repeat Locus in the Context of Its Flanking Sequence
Mol. Biol. Evol., November 1, 2002; 19(11): 1943 - 1951.
[Abstract] [Full Text] [PDF]