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Molecular Biology and Evolution 17:1410-1412 (2000)
© 2000 Society for Molecular Biology and Evolution

Letter to the Editor

Nuclear Gene LCAT Supports Rodent Monophyly

Marc Robinson-Rechavi*2,, Loïc Ponger{dagger} and Dominique Mouchiroud{dagger}

*Laboratoire de Biologie Moleculaire et Cellulaire, Ecole Normale Superieure de Lyon, Lyon, France; and
{dagger}Laboratoire de Biométrie et Biologie Evolutive, Université Claude Bernard—Lyon 1, Villeurbanne cedex, France

Rodents (order Rodentia) have attracted much attention from molecular evolution studies. Rats and mice, and, to a lesser extent, guinea pigs and hamsters, are widely used models in molecular and cellular biology, which has made their sequences widely available. Strong focus has been on determining whether or not rodents are monophyletic (Graur, Hide, and Li 1991Citation ; Luckett and Hartenberger 1993Citation ; d'Erchia et al. 1996Citation ; Cao, Okada, and Hasegawa 1997Citation ), turning the question into a battleground of different approaches of mammalian phylogeny.

A large number of studies do not resolve the question of rodent monophyly, despite an abundance of data, including reanalyses of the data from Graur, Hide, and Li (1991)Citation with maximum likelihood (Hasegawa et al. 1992Citation ; Li, Hide, and Graur 1992Citation ; Cao et al. 1994Citation ), cytochrome b, cytochrome oxidase c, and 12S rRNA sequences from large samples of mammals (Ma et al. . . . [Full Text of this Article]


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