Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (40)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Macey, J. R.
Right arrow Articles by Papenfuss, T. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Macey, J. R.
Right arrow Articles by Papenfuss, T. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution, Vol 14, 30-39, Copyright © 1997 by Society for Molecular Biology and Evolution

ORIGINAL ARTICLE

Replication slippage may cause parallel evolution in the secondary structures of mitochondrial transfer RNAs

JR Macey, A Larson, NB Ananjeva and TJ Papenfuss
Department of Biology, Washington University, St. Louis, Missouri 63130, USA.

Presence of the dihydrouridine (D) stem in the mitochondrial cysteine tRNA is unusually variable among lepidosaurian reptiles. Phylogenetic and comparative analyses of cysteine tRNA gene sequences identify eight parallel losses of the D-stem, resulting in D-arm replacement loops. Sampling within the monophyletic Acrodonta provides no evidence for reversal. Slipped-strand mispairing of noncontiguous repeated sequences during replication or direct replication slippage can explain repeats observed within cysteine tRNAs that contain a D-arm replacement loop. These two mechanisms involving replication slippage can account for the loss of the cysteine tRNA D-stem in several lepidosaurian lineages, and may represent general mechanisms by which the secondary structures of mitochondrial tRNAs are altered.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Mol Biol EvolHome page
A. Stoltzfus
Mutation-Biased Adaptation in a Protein NK Model
Mol. Biol. Evol., October 1, 2006; 23(10): 1852 - 1862.
[Abstract] [Full Text] [PDF]

Home page
 Syst BiolHome page
D. W. Weisrock, L. J. Harmon, and A. Larson
Resolving Deep Phylogenetic Relationships in Salamanders: Analyses of Mitochondrial and Nuclear Genomic Data
Syst Biol, October 1, 2005; 54(5): 758 - 777.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
R. L. Mueller and J. L. Boore
Molecular Mechanisms of Extensive Mitochondrial Gene Rearrangement in Plethodontid Salamanders
Mol. Biol. Evol., October 1, 2005; 22(10): 2104 - 2112.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
S. E. Masta
Mitochondrial Sequence Evolution in Spiders: Intraspecific Variation in tRNAs Lacking the T{Psi}C Arm
Mol. Biol. Evol., July 1, 2000; 17(7): 1091 - 1100.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
A. Kurabayashi and R. Ueshima
Complete Sequence of the Mitochondrial DNA of the Primitive Opisthobranch Gastropod Pupa strigosa: Systematic Implication of the Genome Organization
Mol. Biol. Evol., February 1, 2000; 17(2): 266 - 277.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.