Molecular Biology and Evolution 18:1823-1827 (2001)
© 2001 Society for Molecular Biology and Evolution
Traditional Phylogenetic Reconstruction Methods Reconstruct Shallow and Deep Evolutionary Relationships Equally Well
Department of Biology, Arizona State University
The wealth of data available for molecular phylogenetic analyses is expanding at an exponential pace. As data sets have become larger, it has become increasingly critical to understand the advantages and disadvantages of using various phylogenetic inference methods. Four inference methods based on three optimization criteria are commonly used to reconstruct evolutionary history from molecular data: neighbor joining (NJ), minimum evolution (ME), maximum parsimony (MP), and maximum likelihood (ML). The overall efficiency and performance of these methods in reconstructing the true tree is known to vary with substitution rate, transition-transversion ratio, and sequence divergence (Miyamoto and Cracraft 1991
; Nei and Kumar 2000
).
Computer simulation has proven to be an excellent means of assessing the performance of tree-building methods (reviewed in Nei and Kumar 2000
, chapter 9). It can be used to examine the overall performance of a method or specific aspects of its performance (e.g., Hillis 1996
Acknowledgements
Footnotes
References
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
M. S. Rosenberg and S. Kumar Heterogeneity of Nucleotide Frequencies Among Evolutionary Lineages and Phylogenetic Inference Mol. Biol. Evol., April 1, 2003; 20(4): 610 - 621. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. S. Rosenberg and S. Kumar Incomplete taxon sampling is not a problem for phylogenetic inference PNAS, August 23, 2001; (2001) 191248498. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. S. Rosenberg and S. Kumar Incomplete taxon sampling is not a problem for phylogenetic inference PNAS, September 11, 2001; 98(19): 10751 - 10756. [Abstract] [Full Text] [PDF] |
||||

