Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (10)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Iwase, M.
Right arrow Articles by Takahata, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Iwase, M.
Right arrow Articles by Takahata, N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution 18:1601-1603 (2001)
© 2001 Society for Molecular Biology and Evolution

Sex-Chromosomal Differentiation and Amelogenin Genes in Mammals

Mineyo Iwase, Yoko Satta and Naoyuki Takahata

Department of Biosystems Science, Graduate University for Advanced Studies, Hayama, Kanagawa, Japan

Paralogous gene pairs on the mammalian sex chromosomes can provide useful information on the tempo and mode of X-Y differentiation. Recently, Lahn and Page (1999)Citation reported intriguing results on the chromosomal locations and synonymous sequence divergences (ks with multiple-hit correction) of 19 pairs of X-Y-paralogous cDNA sequences in humans or squirrel monkeys. It was found that there are four distinct groups (strata) of the gene pairs in terms of the ks value. Of these, seven belong to stratum 4, and the X paralogs are clustered in a single chromosomal region which is adjacent to the pseudoautosomal boundary in the short arm of chromosome X. In contrast, the seven Y paralogs are scattered on chromosome Y, presumably owing to frequent chromosomal rearrangements. Together with similar observations on strata 1, 2, and 3, it was hypothesized that X-Y-chromosomal differentiation was initiated one stratum at a time and that stratum 1 was . . . [Full Text of this Article]

Acknowledgements

Footnotes

References


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Dent. Res.Home page
S. Delgado, M. Ishiyama, and J.-Y. Sire
Validation of Amelogenesis Imperfecta Inferred from Amelogenin Evolution
J. Dent. Res., April 1, 2007; 86(4): 326 - 330.
[Abstract] [Full Text] [PDF]

Home page
 J. Dent. Res.Home page
T. Ikawa, A. Kakegawa, T. Nagano, H. Ando, Y. Yamakoshi, T. Tanabe, J.P. Simmer, C.-C. Hu, M. Fukae, and S. Oida
Porcine Amelogenin is Expressed from the X and Y Chromosomes
J. Dent. Res., February 1, 2005; 84(2): 144 - 148.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
S. A. Sandstedt and P. K. Tucker
Evolutionary Strata on the Mouse X Chromosome Correspond to Strata on the Human X Chromosome
Genome Res., February 1, 2004; 14(2): 267 - 272.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Iwase, Y. Satta, Y. Hirai, H. Hirai, H. Imai, and N. Takahata
From the Cover: The amelogenin loci span an ancient pseudoautosomal boundary in diverse mammalian species
PNAS, April 29, 2003; 100(9): 5258 - 5263.
[Abstract] [Full Text] [PDF]