Molecular Biology and Evolution 17:984-986 (2000)
© 2000 Society for Molecular Biology and Evolution
Letter to the Editor |
Master Copy Is Not Responsible for the High Rate of copia Transposition in Drosophila
Section of Evolution and Ecology, University of California at Davis
The genome of Drosophila melanogaster—a model species for studying transposable element (TE) population dynamics—contains approximately 50 different families classified as transposons, long interspersed nuclear element (LINE)–type elements, and long terminal repeat (LTR)–containing retrotransposons that resemble viruses. There are, on average, 20 copies per family, with a few base pairs different between copies within a family (Charlesworth, Sniegowski, and Stephan 1994
). copia and gypsy—the best studied LTR elements—are inactive in most laboratory lines. However, in several transposition-susceptible lines, they produce on the order of one new copy per genome per generation (for reviews, see Pelisson et al. 1997
; Pasyukova, Nuzhdin, and Filatov 1998
). Complex interactions between elements and host genes are responsible for susceptibility. In the case of gypsy elements, a copy of a permissive flamenco allele and a specific "rogue" sequence variant of gypsy are required in the maternal genome for transpositions to occur in
 |
Acknowledgements |
|---|
|
Footnotes |
|---|
|
literature cited |
|---|
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M. Papaceit, V. Avila, M. Aguade, and A. Garcia-Dorado The Dynamics of the roo Transposable Element In Mutation-Accumulation Lines and Segregating Populations of Drosophila melanogaster Genetics, September 1, 2007; 177(1): 511 - 522. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Lopez-Sanchez, J. C. Costas, and H. F. Naveira Paleogenomic Record of the Extinction of Human Endogenous Retrovirus ERV9 J. Virol., June 1, 2005; 79(11): 6997 - 7004. [Abstract] [Full Text] [PDF]
|
|