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MBE Advance Access published online on October 23, 2009
Molecular Biology and Evolution, doi:10.1093/molbev/msp259
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© The Author 2009. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Letter

SeaView version 4 : a multiplatform graphical user interface for sequence alignment and phylogenetic tree building

Manolo Gouy1,*, Stéphane Guindon2,3 and Olivier Gascuel2

1 Laboratoire de Biométrie et Biologie Evolutive, CNRS UMR 5558, Université Lyon 1, Université de Lyon, 43 boulevard du 11 Novembre 1918, 69622 Villeurbanne, France
2 Méthodes et Algorithmes pour la Bioinformatique, LIRMM, CNRS UMR 5506, Université Montpellier II, 161 rue Ada, 34392 Montpellier, France
3 Department of Statistics, University of Auckland, Auckland, 1142, New Zealand

* Corresponding author, E-mail: mgouy{at}biomserv.univ-lyon1.fr, Fax: +33 4 72 43 13 88; Tel: +33 4 72 43 12 87, Postal address : Biométrie et Biologie Evolutive, Université Lyon 1, 43 Boulevard du 11 Novembre, 69622 Villeurbanne, France.

Received for publication August 28, 2009. Revision received October 19, 2009. Accepted for publication October 20, 2009.

We present SeaView version 4, a multiplatform program designed to facilitate multiple alignment and phylogenetic tree building from molecular sequence data through the use of a graphical user interface. SeaView version 4 combines all the functions of the widely used programs SeaView (in its previous versions) and Phylo_win, and expands them by adding network access to sequence databases, alignment with arbitrary algorithm, maximum likelihood tree-building with PhyML, and display, printing, and copy-to-clipboard of rooted or unrooted, binary or multifurcating phylogenetic trees. In relation to the wide present offer of tools and algorithms for phylogenetic analyses, SeaView is especially useful for teaching and for occasional users of such software. SeaView is freely available at http://pbil.univ-lyon1.fr/software/seaview.

Key Words: SeaView • multiple sequence alignment • molecular phylogeny • PhyML • Graphical User Interface


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