Molecular Biology and Evolution, Vol 9, 688-706, Copyright © 1992 by Society for Molecular Biology and Evolution
BG Hall and L Xu
The cryptic asc (previous called "SAC") operon of Escherichia coli K12 has
been completely sequenced. It encodes a repressor (ascG); a PTS enzyme
IIasc for the transport of arbutin, salicin, and cellobiose (ascF); and a
phospho-beta-glucosidase that hydrolyzes the sugars which are
phosphorylated during transport (ascB). ascG and ascFB are transcribed from
divergent promoters. The cryptic operon is activated by the insertion of
IS186 into the ascG (repressor) gene. The ascFB genes are paralogous to the
cryptic bglFB genes, and ascG is paralogous to galR. The duplications that
gave rise to these paralogous genes are estimated to have occurred
approximately 320 Mya, a time that predates the divergence of E. coli and
Salmonella typhimurium.
ORIGINAL ARTICLE
Nucleotide sequence, function, activation, and evolution of the cryptic asc operon of Escherichia coli K12
Biology Department, University of Rochester, New York 14627.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  Y. Ishida, A. Kori, and A. Ishihama Participation of Regulator AscG of the {beta}-Glucoside Utilization Operon in Regulation of the Propionate Catabolism Operon J. Bacteriol., October 1, 2009; 191(19): 6136 - 6144. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Neelakanta, T. S. Sankar, and K. Schnetz Characterization of a {beta}-Glucoside Operon (bgc) Prevalent in Septicemic and Uropathogenic Escherichia coli Strains Appl. Envir. Microbiol., April 15, 2009; 75(8): 2284 - 2293. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Monderer-Rothkoff and O. Amster-Choder Genetic Dissection of the Divergent Activities of the Multifunctional Membrane Sensor BglF J. Bacteriol., December 1, 2007; 189(23): 8601 - 8615. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Yuan, I. Kurek, J. English, and R. Keenan Laboratory-Directed Protein Evolution Microbiol. Mol. Biol. Rev., September 1, 2005; 69(3): 373 - 392. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. M. Bennett, C. T. Livesey, D. Nathwani, D. S. Reeves, J. R. Saunders, and R. Wise An assessment of the risks associated with the use of antibiotic resistance genes in genetically modified plants: report of the Working Party of the British Society for Antimicrobial Chemotherapy J. Antimicrob. Chemother., March 1, 2004; 53(3): 418 - 431. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Kotrba, M. Inui, and H. Yukawa A single V317A or V317M substitution in Enzyme II of a newly identified {beta}-glucoside phosphotransferase and utilization system of Corynebacterium glutamicum R extends its specificity towards cellobiose Microbiology, June 1, 2003; 149(6): 1569 - 1580. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. K. Cote and A. L. Honeyman The LicT protein acts as both a positive and a negative regulator of loci within the bgl regulon of Streptococcus mutans Microbiology, May 1, 2003; 149(5): 1333 - 1340. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S.-p. Hung, P. Baldi, and G. W. Hatfield Global Gene Expression Profiling in Escherichia coli K12. THE EFFECTS OF LEUCINE-RESPONSIVE REGULATORY PROTEIN J. Biol. Chem., October 18, 2002; 277(43): 40309 - 40323. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Moorthy and S. Mahadevan Differential Spectrum of Mutations That Activate the Escherichia coli bgl Operon in an rpoS Genetic Background J. Bacteriol., July 15, 2002; 184(14): 4033 - 4038. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. G. Hall Predicting Evolutionary Potential. I. Predicting the Evolution of a Lactose-PTS System in Escherichia coli Mol. Biol. Evol., July 1, 2001; 18(7): 1389 - 1400. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. McClelland, L. Florea, K. Sanderson, S. W. Clifton, J. Parkhill, C. Churcher, G. Dougan, R. K. Wilson, and W. Miller Comparison of the Escherichia coli K-12 genome with sampled genomes of a Klebsiella pneumoniae and three Salmonella enterica serovars, Typhimurium, Typhi and Paratyphi Nucleic Acids Res., December 15, 2000; 28(24): 4974 - 4986. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. A. Weber, J. R. Klein, and B. Henrich Expression of the phospho-{beta}-glycosidase ArbZ from Lactobacillus delbrueckii subsp. lactis in Lactobacillus helveticus: substrate induction and catabolite repression Microbiology, August 1, 2000; 146(8): 1941 - 1948. [Abstract] [Full Text]
|
|
|
|
|
|
A. S. Kharat and S. Mahadevan Analysis of the {beta}-glucoside utilization (bgl) genes of Shigella sonnei: evolutionary implications for their maintenance in a cryptic state Microbiology, August 1, 2000; 146(8): 2039 - 2049. [Abstract] [Full Text]
|
|
|
|
|
|
J. Thompson, S. B. Ruvinov, D. I. Freedberg, and B. G. Hall Cellobiose-6-Phosphate Hydrolase (CelF) of Escherichia coli: Characterization and Assignment to the Unusual Family 4 of Glycosylhydrolases J. Bacteriol., December 1, 1999; 181(23): 7339 - 7345. [Abstract] [Full Text]
|
|
|
|
|
|
M. K. B. Berlyn Linkage Map of Escherichia coli K-12, Edition 10: The Traditional Map Microbiol. Mol. Biol. Rev., September 1, 1998; 62(3): 814 - 984. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. R. Smith, P. Richterich, M. Rubenfield, P. W. Rice, C. Butler, H.-M. Lee, S. Kirst, K. Gundersen, K. Abendschan, Q. Xu, et al. Multiplex Sequencing of 1.5 Mb of the Mycobacterium leprae Genome Genome Res., August 1, 1997; 7(8): 802 - 819. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. W. Bauer, E. J. Bylina, R. V. Swanson, and R. M. Kelly Comparison of a beta -Glucosidase and a beta -Mannosidase from the Hyperthermophilic Archaeon Pyrococcus furiosus. PURIFICATION, CHARACTERIZATION, GENE CLONING, AND SEQUENCE ANALYSIS J. Biol. Chem., September 27, 1996; 271(39): 23749 - 23755. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. O. Keyhani, O. Boudker, and S. Roseman Isolation and Characterization of IIAChb, a Soluble Protein of the Enzyme II Complex Required for the Transport/Phosphorylation of N,N'-Diacetylchitobiose in Escherichia coli J. Biol. Chem., October 13, 2000; 275(42): 33091 - 33101. [Abstract] [Full Text] [PDF]
|
|