Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (19)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Jubier-Maurin, V.
Right arrow Articles by Roizes, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jubier-Maurin, V.
Right arrow Articles by Roizes, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution, Vol 9, 41-55, Copyright © 1992 by Society for Molecular Biology and Evolution

ORIGINAL ARTICLE

A new 5' sequence associated with mouse L1 elements is representative of a major class of L1 termini

V Jubier-Maurin, G Cuny, AM Laurent, L Paquereau and G Roizes
CNRS (CRBM-UPR 8402) Inserm U.249, Institut de Biologie, Montpellier, France.

Full-length L1 elements have been shown to possess, at their 5' end, tandem repeats called "A" or "F" types. By sequencing the 5' region of two large L1 copies that did not hybridize to A or F probes, we have identified a new sequence that is found at the 5' end of many L1 elements and that we call "V." The element characterized has no 200-bp tandem repetitive structure, and the new 5' sequence is not similar to the A or F sequences. The study of the relationships between the V and L1 sequences has shown that only half of the V (i.e., V-specific 5') sequences in the genome are linked to the 5' end of L1 copies. In related rodent species, a comparative study by Southern blot and PCR analysis of the V sequence suggests that this L1 subfamily has an ancient origin and that V sequence isolated from the remainder of the L1 element has been amplified during the evolution of the mouse genome.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Genome ResHome page
H. Khan, A. Smit, and S. Boissinot
Molecular evolution and tempo of amplification of human LINE-1 retrotransposons since the origin of primates
Genome Res., January 1, 2006; 16(1): 78 - 87.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
K. P. Lu and K. S. Ramos
Redox Regulation of a Novel L1Md-A2 Retrotransposon in Vascular Smooth Muscle Cells
J. Biol. Chem., July 18, 2003; 278(30): 28201 - 28209.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. V. Furano and K. Usdin
DNA ``Fossils'' and Phylogenetic Analysis
J. Biol. Chem., October 27, 1995; 270(43): 25301 - 25304.
[Full Text] [PDF]

Home page
 Genome ResHome page
J. L. Goodier, E. M. Ostertag, K. Du, and H. H. Kazazian Jr.
A Novel Active L1 Retrotransposon Subfamily in the Mouse
Genome Res., October 1, 2001; 11(10): 1677 - 1685.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.