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Molecular Biology and Evolution, Vol 6, 325-330, Copyright © 1989 by Society for Molecular Biology and Evolution

ORIGINAL ARTICLE

A statistical test that supports a human/chimpanzee clade based on noncoding DNA sequence data

SA Williams and M Goodman
Department of Mathematics, Wayne State University, Detroit, Michigan 48202.

Using the aligned DNA sequence data of Miyamoto et al. and Maeda et al., all noncoding genetic material, and a simple statistical test, we show that a Homo/Pan clade is supported at approximately the 3% level of significance. The method accommodates polymorphism and different evolutionary rates for different sites. All assumptions on which the statistical study is based are made explicit. (See the Note added in proof, which--adding recently published data--improves the significance level to about 1%.
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