Skip Navigation


MBE Advance Access originally published online on October 16, 2006
Molecular Biology and Evolution 2007 24(1):1-5; doi:10.1093/molbev/msl136
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
24/1/1    most recent
msl136v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Abascal, F.
Right arrow Articles by Zardoya, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Abascal, F.
Right arrow Articles by Zardoya, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Letters

MtArt: A New Model of Amino Acid Replacement for Arthropoda

Federico Abascal*,{dagger}, David Posada* and Rafael Zardoya{dagger}

* Departamento de Bioquímica, Genética e Inmunología, Universidad de Vigo, Vigo, Spain
{dagger} Departamento de Biodiversidad y Biología Evolutiva, Museo Nacional de Ciencias Naturales, Madrid, Spain

E-mail: rafaz{at}mncn.csic.es.

Accepted for publication September 25, 2006.

A statistical approach was applied to select those models that best fit each individual mitochondrial (mt) protein at different taxonomic levels of metazoans. The existing mitochondrial replacement matrices, MtREV and MtMam, were found to be the best-fit models for the mt-proteins of vertebrates, with the exception of Nd6, at different taxonomic levels. Remarkably, existing mitochondrial matrices generally failed to best-fit invertebrate mt-proteins. In an attempt to better model the evolution of invertebrate mt-proteins, a new replacement matrix, named MtArt, was constructed based on arthropod mt-proteomes. The new model was found to best fit almost all analyzed invertebrate mt-protein data sets. The observed pattern of model fit across the different data sets indicates that no single replacement matrix is able to describe the general evolutionary properties of mt-proteins but rather that taxonomical biases and/or the existence of different mt–genetic codes have great influence on which model is selected.

Key Words: mitochondrial genomes • protein evolution • model selection • amino acid replacement matrix • arthropods

Sudhir Kumar, Associate Editor


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Mol Biol EvolHome page
W. Fletcher and Z. Yang
INDELible: A Flexible Simulator of Biological Sequence Evolution
Mol. Biol. Evol., August 1, 2009; 26(8): 1879 - 1888.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
S. Q. Le and O. Gascuel
An Improved General Amino Acid Replacement Matrix
Mol. Biol. Evol., July 1, 2008; 25(7): 1307 - 1320.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
J. A. Servin, C. W. Herbold, R. G. Skophammer, and J. A. Lake
Evidence Excluding the Root of the Tree of Life from the Actinobacteria
Mol. Biol. Evol., January 1, 2008; 25(1): 1 - 4.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.