Skip Navigation


MBE Advance Access originally published online on May 25, 2005
Molecular Biology and Evolution 2005 22(9):1793-1801; doi:10.1093/molbev/msi175
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
22/9/1793    most recent
msi175v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (18)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Jagadeeshan, S.
Right arrow Articles by Singh, R. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jagadeeshan, S.
Right arrow Articles by Singh, R. S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oupjournals.org

Research Article

Rapidly Evolving Genes of Drosophila: Differing Levels of Selective Pressure in Testis, Ovary, and Head Tissues Between Sibling Species

Santosh Jagadeeshan and Rama S. Singh

Department of Biology, McMaster University, Hamilton, Ontario, Canada

E-mail: singh{at}mcmaster.ca.

Investigations of rapidly evolving sex- and reproduction-related genes are expected to reveal important information about the process of speciation and species divergence. We screened testis, ovary, and head tissues to identify and characterize rapidly evolving genes (REGs) between closely related species. The results show differential patterns of evolution of genes expressed in reproductive and nonreproductive tissues. (1) There is a differential distribution of REGs in the Drosophila genome, with most REGs localized in the testis, followed by ovary, and then head. (2) Sequence analysis indicates that differential selective pressures are driving the rapid evolution of genes expressed in sex and nonsex tissues. Testis REGs from our data, on average, yielded higher rates of nonsynonymous substitutions relative to transcripts in ovary and head, indicating stronger selective pressures on the male reproductive system. (3) We identified REGs in the testis, ovary, as well as in head tissue that show evidence of evolving under positive selection. Identification of rapidly evolving sex genes is important for detailed investigations of cryptic female choice, sexual conflict, and faster male evolution and is pertinent to our understanding of the process of species divergence and speciation.

Key Words: speciation • sexual selection • sex- and reproduction-related genes • rapidly evolving genes


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 GeneticsHome page
L. M. Mikhaylova, K. Nguyen, and D. I. Nurminsky
Analysis of the Drosophila melanogaster Testes Transcriptome Reveals Coordinate Regulation of Paralogous Genes
Genetics, May 1, 2008; 179(1): 305 - 315.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
C. G. Artieri, W. Haerty, B. P. Gupta, and R. S. Singh
Sexual Selection and Maintenance of Sex: Evidence from Comparisons of Rates of Genomic Accumulation of Mutations and Divergence of Sex-Related Genes in Sexual and Hermaphroditic Species of Caenorhabditis
Mol. Biol. Evol., May 1, 2008; 25(5): 972 - 979.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
J. E. Mank, L. Hultin-Rosenberg, E. Axelsson, and H. Ellegren
Rapid Evolution of Female-Biased, but Not Male-Biased, Genes Expressed in the Avian Brain
Mol. Biol. Evol., December 1, 2007; 24(12): 2698 - 2706.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
W. Haerty, S. Jagadeeshan, R. J. Kulathinal, A. Wong, K. Ravi Ram, L. K. Sirot, L. Levesque, C. G. Artieri, M. F. Wolfner, A. Civetta, et al.
Evolution in the Fast Lane: Rapidly Evolving Sex-Related Genes in Drosophila
Genetics, November 1, 2007; 177(3): 1321 - 1335.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
R. M. Graze, O. Barmina, D. Tufts, E. Naderi, K. L. Harmon, M. Persianinova, and S. V. Nuzhdin
New Candidate Genes for Sex-Comb Divergence Between Drosophila mauritiana and Drosophila simulans
Genetics, August 1, 2007; 176(4): 2561 - 2576.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
S. Jagadeeshan and R. S. Singh
Rapid Evolution of Outer Egg Membrane Proteins in the Drosophila melanogaster Subgroup: A Case of Ecologically Driven Evolution of Female Reproductive Traits
Mol. Biol. Evol., April 1, 2007; 24(4): 929 - 938.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
V. L. Bauer DuMont, H. A. Flores, M. H. Wright, and C. F. Aquadro
Recurrent Positive Selection at Bgcn, a Key Determinant of Germ Line Differentiation, Does Not Appear to be Driven by Simple Coevolution with Its Partner Protein Bam
Mol. Biol. Evol., January 1, 2007; 24(1): 182 - 191.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
M. Metta, R. Gudavalli, J.-M. Gibert, and C. Schlotterer
No Accelerated Rate of Protein Evolution in Male-Biased Drosophila pseudoobscura Genes
Genetics, September 1, 2006; 174(1): 411 - 420.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
W. Haerty and R. S. Singh
Gene Regulation Divergence Is a Major Contributor to the Evolution of Dobzhansky-Muller Incompatibilities between Species of Drosophila
Mol. Biol. Evol., September 1, 2006; 23(9): 1707 - 1714.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
L. M. Turner and H. E. Hoekstra
Adaptive Evolution of Fertilization Proteins within a Genus: Variation in ZP2 and ZP3 in Deer Mice (Peromyscus)
Mol. Biol. Evol., September 1, 2006; 23(9): 1656 - 1669.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.