Skip Navigation


MBE Advance Access originally published online on December 29, 2004
Molecular Biology and Evolution 2005 22(4):905-913; doi:10.1093/molbev/msi074
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
22/4/905    most recent
msi074v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Rzhetsky, A.
Right arrow Articles by Fitch, W. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rzhetsky, A.
Right arrow Articles by Fitch, W. M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution vol. 22 no. 4 © Society for Molecular Biology and Evolution 2004; all rights reserved.

Research Article

Listening to Viral Tongues: Comparing Viral Trees Using a Stochastic Context-Free Grammar

Andrey Rzhetsky* and Walter M. Fitch{dagger}

* Department of Biomedical Informatics, Columbia Genome Center, and Center for Computational Biology and Bioinformatics, Columbia University, New York; and {dagger} Department of Ecology and Evolutionary Biology, University of California, Irvine

E-mail: wfitch{at}uci.edu.

We suggest a probabilistic method for comparing the topological features of large phylogenetic trees. Using this method, we demonstrate that a stochastic grammar can generate three influenza-subtype (A H1, A H3, and B) hemagglutinin trees used in an earlier study, with statistically similar parameters. The proposed methodology is applicable to a broad class of problems that require comparison of the topological properties of various dendrograms.

Key Words: stochastic context-free grammar • human influenza virus hemagglutinin • stochastic measures of tree similarity • multitype branching processes


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.