Skip Navigation


MBE Advance Access originally published online on May 21, 2004
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Data Supplement
Right arrow All Versions of this Article:
21/8/1602    most recent
msh164v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (7)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Moury, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Moury, B.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Mol. Biol. Evol. 21(8):1602-1611. 2004
DOI: 10.1093/molbev/msh164
© 2004 by the Society for Molecular Biology and Evolution. ISSN: 0737-4038

Differential Selection of Genes of Cucumber Mosaic Virus Subgroups

Benoît Moury

Station de Pathologie Végétale, Institut National de la Recherche Agronomique, Montfavet Cedex, France

E-mail: moury{at}avignon.inra.fr.

Cucumber mosaic virus (CMV) has an extremely broad plant-host range, a large number of vector species, and a wide geographical distribution. CMV is, therefore, a model by which to understand plant virus adaptation. The selective constraints exerted on the five proteins expressed from the CMV genome were evaluated by application of newly developed maximum-likelihood algorithms to analyze sequences available in data banks. The ratio between nonsynonymous and synonymous substitution rates ({omega}) was used to detect positive selection on particular codon sites. Amino acid sequences were conserved with {omega} ranging from 0.07 to 0.60 in different proteins. However, a small proportion of amino acids in proteins 1a, 2a, and 3b, the coat protein (CP), were positively selected ({omega} > 1). Moreover, the evolution of the CP in the three subgroups of CMV strains revealed different selection profiles along the sequence and significantly different speed of evolution at many positions. Constraints exerted by aphid transmission, rather than plant adaptation, seemed to be responsible for these patterns of evolution in the CP.

Key Words: positive selection • cucumber mosaic virus • Cucumovirus • insect transmission • epidemiology


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
B. Moury, F. Fabre, and R. Senoussi
Estimation of the number of virus particles transmitted by an insect vector
PNAS, November 6, 2007; 104(45): 17891 - 17896.
[Abstract] [Full Text] [PDF]

Home page
 J. Gen. Virol.Home page
G. Hall
Selective constraint and genetic differentiation in geographically distant barley yellow dwarf virus populations.
J. Gen. Virol., October 1, 2006; 87(Pt 10): 3067 - 3075.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
D. J. Wilson and G. McVean
Estimating Diversifying Selection and Functional Constraint in the Presence of Recombination
Genetics, March 1, 2006; 172(3): 1411 - 1425.
[Abstract] [Full Text] [PDF]

Home page
 J. Gen. Virol.Home page
A. Schirmer, D. Link, V. Cognat, B. Moury, M. Beuve, A. Meunier, C. Bragard, D. Gilmer, and O. Lemaire
Phylogenetic analysis of isolates of Beet necrotic yellow vein virus collected worldwide
J. Gen. Virol., October 1, 2005; 86(10): 2897 - 2911.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
Z. Yang, W. S.W. Wong, and R. Nielsen
Bayes Empirical Bayes Inference of Amino Acid Sites Under Positive Selection
Mol. Biol. Evol., April 1, 2005; 22(4): 1107 - 1118.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.