Skip Navigation


MBE Advance Access originally published online on January 22, 2004
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Supplementary Material
Right arrow All Versions of this Article:
21/5/781    most recent
msh057v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (13)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Gorinsek, B.
Right arrow Articles by Kordis, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gorinsek, B.
Right arrow Articles by Kordis, D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Mol. Biol. Evol. 21(5):781-798. 2004
DOI: 10.1093/molbev/msh057
© 2004 by the Society for Molecular Biology and Evolution. ISSN: 0737-4038

Evolutionary Genomics of Chromoviruses in Eukaryotes

Benjamin Gorinsek*, Franc Gubensek*,{dagger} and Dusan Kordis*

* Department of Biochemistry and Molecular Biology, Joef Stefan Institute, Ljubljana, Slovenia
{dagger} Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia

E-mail: dusan.kordis{at}ijs.si.

The diversity, origin, and evolution of chromoviruses in Eukaryota were examined using the massive amount of genome sequence data for different eukaryotic lineages. A surprisingly large number of novel full-length chromoviral elements were found, greatly exceeding the number of the known chromoviruses. These new elements are mostly structurally intact and highly conserved. Chromoviruses in the key Amniota lineage, the reptiles, have been analyzed by PCR to explain their evolutionary dynamics in amniotes. Phylogenetic analyses provide evidence for a novel centromere-specific chromoviral clade that is widespread and highly conserved in all seed plants. Chromoviral diversity in plants, fungi, and vertebrates, as shown by phylogenetic analyses, was found to be much greater than previously expected. The age of plant chromoviruses has been significantly extended by finding their representatives in the most basal plant lineages, the green and the red algae. The evolutionary origin of chromoviruses has been found to be no earlier than in Cercozoa. The evolutionary history and dynamics of chromoviruses can be explained simply by strict vertical transmission in plants, followed by more complex evolution in fungi and in Metazoa. The currently available data clearly show that chromoviruses indeed represent the oldest and the most widespread clade of Metaviridae.

Key Words: Chromovirus • retrotransposon • gypsy • evolutionary genomics


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Genome ResHome page
X. Gao, Y. Hou, H. Ebina, H. L. Levin, and D. F. Voytas
Chromodomains direct integration of retrotransposons to heterochromatin
Genome Res., March 1, 2008; 18(3): 359 - 369.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
C. Llorens, R. Futami, D. Bezemer, and A. Moya
The Gypsy Database (GyDB) of mobile genetic elements
Nucleic Acids Res., January 11, 2008; 36(suppl_1): D38 - D46.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
P. Neumann, H. Yan, and J. Jiang
The Centromeric Retrotransposons of Rice Are Transcribed and Differentially Processed by RNA Interference
Genetics, June 1, 2007; 176(2): 749 - 761.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. Hizi and H. L. Levin
The Integrase of the Long Terminal Repeat-Retrotransposon Tf1 Has a Chromodomain That Modulates Integrase Activities
J. Biol. Chem., November 25, 2005; 280(47): 39086 - 39094.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
A.-C. Andersson, Z. Yun, G. O. Sperber, E. Larsson, and J. Blomberg
ERV3 and Related Sequences in Humans: Structure and RNA Expression
J. Virol., July 15, 2005; 79(14): 9270 - 9284.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
K. Nagaki, P. Neumann, D. Zhang, S. Ouyang, C. R. Buell, Z. Cheng, and J. Jiang
Structure, Divergence, and Distribution of the CRR Centromeric Retrotransposon Family in Rice
Mol. Biol. Evol., April 1, 2005; 22(4): 845 - 855.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.