Skip Navigation


MBE Advance Access originally published online on June 27, 2003
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
20/9/1521    most recent
msg164v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (9)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Ebner, B.
Right arrow Articles by Hankeln, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ebner, B.
Right arrow Articles by Hankeln, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Mol. Biol. Evol. 20(9):1521-1525. 2003
DOI: 10.1093/molbev/msg164
© 2003 by the Society for Molecular Biology and Evolution. ISSN: 0737-4038

Globin Genes Are Present in Ciona intestinalis

Bettina Ebner*, Thorsten Burmester{dagger} and Thomas Hankeln*,

* Institute of Molecular Genetics
{dagger} Institute of Zoology, Johannes Gutenberg University, Mainz, Germany

E-mail: hankeln{at}uni-mainz.de.

The key position of the Ciona intestinalis basal to the vertebrate phylogenetic tree brings up the question of which respiratory proteins are used by the tunicate to facilitate oxygen transport and storage. The publication of the Ciona draft genome sequence suggests that globin genes are completely missing and that—like some molluscs and arthropods—the sea squirt uses hemocyanin instead of hemoglobin for respiration. However, we report here the presence and expression of at least four distinct globin gene/protein sequences in Ciona. This finding is in agreement with the ancestral phylogeny of the vertebrate globins. Moreover, it seems likely that the Ciona hemocyanin-like sequences have enzymatic instead of respiratory functions.

Key Words: Ciona intestinalis • hemoglobin • neuroglobin • cytoglobin • hemocyanin • intron


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
S. Dewilde, B. Ebner, E. Vinck, K. Gilany, T. Hankeln, T. Burmester, J. Kreiling, C. Reinisch, J. R. Vanfleteren, L. Kiger, et al.
The Nerve Hemoglobin of the Bivalve Mollusc Spisula solidissima: MOLECULAR CLONING, LIGAND BINDING STUDIES, AND PHYLOGENETIC ANALYSIS
J. Biol. Chem., March 3, 2006; 281(9): 5364 - 5372.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. N. Vinogradov, D. Hoogewijs, X. Bailly, R. Arredondo-Peter, M. Guertin, J. Gough, S. Dewilde, L. Moens, and J. R. Vanfleteren
Three globin lineages belonging to two structural classes in genomes from the three kingdoms of life
PNAS, August 9, 2005; 102(32): 11385 - 11389.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
A. Roesner, C. Fuchs, T. Hankeln, and T. Burmester
A Globin Gene of Ancient Evolutionary Origin in Lower Vertebrates: Evidence for Two Distinct Globin Families in Animals
Mol. Biol. Evol., January 1, 2005; 22(1): 12 - 20.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.