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MBE Advance Access originally published online on May 30, 2003
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Mol. Biol. Evol. 20(8):1326-1328. 2003
DOI: 10.1093/molbev/msg145
© 2003 by the Society for Molecular Biology and Evolution. ISSN: 0737-4038

The Effect of Positive Selection on a Sexual Reproduction Gene in Thalassiosira weissflogii (Bacillariophyta): Results Obtained from Maximum-Likelihood and Parsimony-Based Methods

Ulf Sorhannus

Department of Biology and Health Services, Edinboro University of Pennsylvania

E-mail: usorhannus{at}edinboro.edu.

Maximum-Likelihood–based and parsimony-based methods were used to test for potential effects of positive selection on the sexually induced gene 1 (Sig1) in Thalassiosira weissflogii. The Sig proteins are thought to play a role in mediating sperm-egg recognition during the sexual reproduction phase. The results obtained from parsimony-based analyses showed that none of the amino acid sites were influenced by positive selection. Maximum-likelihood analyses indicated that positive selection was affecting a maximum of seven and a minimum of four amino acid sites in the polypeptide derived from Sig1. It was concluded that the results obtained from the maximum-likelihood–based method are more reliable than those obtained from the parsimony-based approach. This is apparently the first study that has shown that reproductive proteins in unicellular eukaryotes are influenced by positive selection.

Key Words: Sexual reproduction gene • likelihood • parsimony • positive selection • synonymous substitution • nonsynonymous substitution


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