Molecular Biology and Evolution, Vol 16, 1341-1346, Copyright © 1999 by Society for Molecular Biology and Evolution
A Losada, JP Abad, M Agudo and A Villasante
Circe is a transposable element recently identified in Drosophila
melanogaster which appears to be mostly associated with the constitutive
heterochromatin. This element shows the structural features of a long
terminal repeat (LTR)-containing retrotransposon: It is flanked by
240-bp-long terminal repeats, and its two open reading frames encode
putative proteins resembling the gag and pol polyproteins of retroviruses.
However, Circe displays striking similarities of both LOA and Ulysses, a
non-LTR element and an LTR element, respectively. The result of its
phylogenetic and structural analysis has allowed us to propose a new
mechanism for non-LTR retrotransposon evolution.
ORIGINAL ARTICLE
The analysis of Circe, an LTR retrotransposon of Drosophila melanogaster, suggests that an insertion of non-LTR retrotransposons into LTR elements can create chimeric retroelements
Centro de Biologia Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain.
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