Molecular Biology and Evolution, Vol 16, 37-48, Copyright © 1999 by Society for Molecular Biology and Evolution
HJ Bandelt, P Forster and A Rohl
Reconstructing phylogenies from intraspecific data (such as human
mitochondrial DNA variation) is often a challenging task because of large
sample sizes and small genetic distances between individuals. The resulting
multitude of plausible trees is best expressed by a network which displays
alternative potential evolutionary paths in the form of cycles. We present
a method ("median joining" [MJ]) for constructing networks from
recombination-free population data that combines features of Kruskal's
algorithm for finding minimum spanning trees by favoring short connections,
and Farris's maximum-parsimony (MP) heuristic algorithm, which sequentially
adds new vertices called "median vectors", except that our MJ method does
not resolve ties. The MJ method is hence closely related to the earlier
approach of Foulds, Hendy, and Penny for estimating MP trees but can be
adjusted to the level of homoplasy by setting a parameter epsilon. Unlike
our earlier reduced median (RM) network method, MJ is applicable to
multistate characters (e.g., amino acid sequences). An additional feature
is the speed of the implemented algorithm: a sample of 800 worldwide mtDNA
hypervariable segment I sequences requires less than 3 h on a Pentium 120
PC. The MJ method is demonstrated on a Tibetan mitochondrial DNA RFLP data
set.
ORIGINAL ARTICLE
Median-joining networks for inferring intraspecific phylogenies
Mathematisches Seminar, Universitat Hamburg, Germany.
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B Kilian, H Ozkan, O Deusch, S Effgen, A Brandolini, J Kohl, W Martin, and F Salamini Independent Wheat B and G Genome Origins in Outcrossing Aegilops Progenitor Haplotypes Mol. Biol. Evol., January 1, 2007; 24(1): 217 - 227. [Abstract] [Full Text] [PDF] |
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G. M Spellman and J. Klicka Testing hypotheses of Pleistocene population history using coalescent simulations: phylogeography of the pygmy nuthatch (Sitta pygmaea) Proc R Soc B, December 22, 2006; 273(1605): 3057 - 3063. [Abstract] [Full Text] [PDF] |
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C. Fraumene, E. M. S. Belle, L. Castri, S. Sanna, G. Mancosu, M. Cosso, F. Marras, G. Barbujani, M. Pirastu, and A. Angius High Resolution Analysis and Phylogenetic Network Construction Using Complete mtDNA Sequences in Sardinian Genetic Isolates Mol. Biol. Evol., November 1, 2006; 23(11): 2101 - 2111. [Abstract] [Full Text] [PDF] |
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D. A. Bolnick, D. I. Bolnick, and D. G. Smith Asymmetric Male and Female Genetic Histories among Native Americans from Eastern North America Mol. Biol. Evol., November 1, 2006; 23(11): 2161 - 2174. [Abstract] [Full Text] [PDF] |
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R. Barnett, N. Yamaguchi, I. Barnes, and A. Cooper The origin, current diversity and future conservation of the modern lion (Panthera leo) Proc R Soc B, September 7, 2006; 273(1598): 2119 - 2125. [Abstract] [Full Text] [PDF] |
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Z. Zhao, N. Yu, Y.-X. Fu, and W.-H. Li Nucleotide Variation and Haplotype Diversity in a 10-kb Noncoding Region in Three Continental Human Populations Genetics, September 1, 2006; 174(1): 399 - 409. [Abstract] [Full Text] [PDF] |
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M. Tapio, N. Marzanov, M. Ozerov, M. Cinkulov, G. Gonzarenko, T. Kiselyova, M. Murawski, H. Viinalass, and J. Kantanen Sheep Mitochondrial DNA Variation in European, Caucasian, and Central Asian Areas Mol. Biol. Evol., September 1, 2006; 23(9): 1776 - 1783. [Abstract] [Full Text] [PDF] |
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M. M. Morin and B. M. E. Moret NETGEN: generating phylogenetic networks with diploid hybrids Bioinformatics, August 1, 2006; 22(15): 1921 - 1923. [Abstract] [Full Text] [PDF] |
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L. Scheinfeldt, F. Friedlaender, J. Friedlaender, K. Latham, G. Koki, T. Karafet, M. Hammer, and J. Lorenz Unexpected NRY Chromosome Variation in Northern Island Melanesia Mol. Biol. Evol., August 1, 2006; 23(8): 1628 - 1641. [Abstract] [Full Text] [PDF] |
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T. Lehmann, P. L. Marcet, D. H. Graham, E. R. Dahl, and J. P. Dubey From the Cover: Globalization and the population structure of Toxoplasma gondii PNAS, July 25, 2006; 103(30): 11423 - 11428. [Abstract] [Full Text] [PDF] |
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M. Fang and L. Andersson Mitochondrial diversity in European and Chinese pigs is consistent with population expansions that occurred prior to domestication Proc R Soc B, July 22, 2006; 273(1595): 1803 - 1810. [Abstract] [Full Text] [PDF] |
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J. S. Johnson, W. S. Laegreid, R. J. Basaraba, and D. C. Baker Truncated gamma-glutamyl carboxylase in rambouillet sheep. Vet. Pathol., July 1, 2006; 43(4): 430 - 437. [Abstract] [Full Text] [PDF] |
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A. E. Pires, L. Ouragh, M. Kalboussi, J. Matos, F. Petrucci-Fonseca, and M. W. Bruford Mitochondrial DNA Sequence Variation in Portuguese Native Dog Breeds: Diversity and Phylogenetic Affinities J. Hered., July 1, 2006; 97(4): 318 - 330. [Abstract] [Full Text] [PDF] |
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