Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (107)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Kruse, M.
Right arrow Articles by Muller, W. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kruse, M.
Right arrow Articles by Muller, W. E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution, Vol 14, 1326-1334, Copyright © 1997 by Society for Molecular Biology and Evolution

ORIGINAL ARTICLE

Early evolution of metazoan serine/threonine and tyrosine kinases: identification of selected kinases in marine sponges

M Kruse, IM Muller and WE Muller
Abteilung fur Angewandte Molekularbiologie, Universitat, Mainz, Germany.

The phylum Porifera (sponges) was the first to diverge from the common ancestor of the Metazoa. In this study, six cDNAs coding for protein- serine/threonine kinases (PS/TKs) are presented; they have been isolated from libraries obtained from the demosponges Geodia cydonium and Suberites domuncula and from the calcareous sponge Sycon raphanus. Sequence alignments of the catalytic domains revealed that two major families of PS/TK, the "conventional" (Ca(2+)-dependent) protein kinase C (PKC), the cPKC subfamily, as well as the "novel" (Ca(2+)- independent) PKC (nPKC), form two separate clusters. In each cluster, the sequence from S. raphanus diverges first. To approach the question about the origin of protein-tyrosine kinases (PTK), which are found only in Metazoa, we analyzed two additional PS/TKs which have been cloned from S. domuncula: the stress-responsive protein kinase (KRSvSD) and the protein-kinase-C-related kinase (PRKvSD). The construction of the phylogenetic tree, comprising the eight PS/TKs and the PTK cloned previously from G. cydonium, revealed that the PTK derived from the branch including the KRSvSD kinase. These data facilitate the first molecular approach to elucidate the origin of metazoan PTK within the PS/TK superfamily.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 JEMHome page
M. Yamamoto, D. M. Standley, S. Takashima, H. Saiga, M. Okuyama, H. Kayama, E. Kubo, H. Ito, M. Takaura, T. Matsuda, et al.
A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3
J. Exp. Med., November 23, 2009; 206(12): 2747 - 2760.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
W. E. G. Muller, A. Boreiko, U. Schlossmacher, X. Wang, C. Eckert, K. Kropf, J. Li, and H. C. Schroder
Identification of a silicatein(-related) protease in the giant spicules of the deep-sea hexactinellid Monorhaphis chuni
J. Exp. Biol., February 1, 2008; 211(3): 300 - 309.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
M. Wiens, M. Korzhev, S. Perovic-Ottstadt, B. Luthringer, D. Brandt, S. Klein, and W. E. G. Muller
Toll-Like Receptors Are Part of the Innate Immune Defense System of Sponges (Demospongiae: Porifera)
Mol. Biol. Evol., March 1, 2007; 24(3): 792 - 804.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
C. Eckert, H. C. Schroder, D. Brandt, S. Perovic-Ottstadt, and W. E.G. Muller
Histochemical and Electron Microscopic Analysis of Spiculogenesis in the Demosponge Suberites domuncula
J. Histochem. Cytochem., September 1, 2006; 54(9): 1031 - 1040.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. A. Nichols, W. Dirks, J. S. Pearse, and N. King
Early evolution of animal cell signaling and adhesion genes
PNAS, August 15, 2006; 103(33): 12451 - 12456.
[Abstract] [Full Text] [PDF]

Home page
 Appl. Environ. Microbiol.Home page
H. C. Schroder, H. J. Breter, E. Fattorusso, H. Ushijima, M. Wiens, R. Steffen, R. Batel, and W. E. G. Muller
Okadaic Acid, an Apoptogenic Toxin for Symbiotic/Parasitic Annelids in the Demosponge Suberites domuncula.
Appl. Envir. Microbiol., July 1, 2006; 72(7): 4907 - 4916.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Wiens, M. Korzhev, A. Krasko, N. L. Thakur, S. Perovic-Ottstadt, H. J. Breter, H. Ushijima, B. Diehl-Seifert, I. M. Muller, and W. E. G. Muller
Innate Immune Defense of the Sponge Suberites domuncula against Bacteria Involves a MyD88-dependent Signaling Pathway: INDUCTION OF A PERFORIN-LIKE MOLECULE
J. Biol. Chem., July 29, 2005; 280(30): 27949 - 27959.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
S. Perovic-Ottstadt, M. Wiens, H.-C. Schroder, R. Batel, M. Giovine, A. Krasko, I. M. Muller, and W. E. G. Muller
Arginine kinase in the demosponge Suberites domuncula: regulation of its expression and catalytic activity by silicic acid
J. Exp. Biol., February 15, 2005; 208(4): 637 - 646.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
W. E. G. Muller, N. L. Thakur, H. Ushijima, A. N. Thakur, A. Krasko, G. Le Pennec, M. M. Indap, S. Perovic-Ottstadt, H. C. Schroder, G. Lang, et al.
Matrix-mediated canal formation in primmorphs from the sponge Suberites domuncula involves the expression of a CD36 receptor-ligand system
J. Cell Sci., May 15, 2004; 117(12): 2579 - 2590.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
M. Wiens, R. Batel, M. Korzhev, and W. E. G. Muller
Retinoid X receptor and retinoic acid response in the marine sponge Suberites domuncula
J. Exp. Biol., September 15, 2003; 206(18): 3261 - 3271.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. C. Schroder, H. Ushijima, A. Krasko, V. Gamulin, N. L. Thakur, B. Diehl-Seifert, I. M. Muller, and W. E. G. Muller
Emergence and Disappearance of an Immune Molecule, an Antimicrobial Lectin, in Basal Metazoa: A TACHYLECTIN-RELATED PROTEIN IN THE SPONGE SUBERITES DOMUNCULA
J. Biol. Chem., August 29, 2003; 278(35): 32810 - 32817.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
W. E. G. Muller, R. Steffen, B. Lorenz, R. Batel, M. Kruse, A. Krasko, I. M. Muller, and H. C. Schroder
Suppression of allograft rejection in the sponge Suberites domuncula by FK506 and expression of genes encoding FK506-binding proteins in allografts
J. Exp. Biol., January 7, 2001; 204(13): 2197 - 2207.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
H. C. SCHRÖDER, A. KRASKO, R. BATEL, A. SKOROKHOD, S. PAHLER, M. KRUSE, I. M. MÜLLER, and W. E. G. MÜLLER
Stimulation of protein (collagen) synthesis in sponge cells by a cardiac myotrophin-related molecule from Suberites domuncula
FASEB J, October 1, 2000; 14(13): 2022 - 2031.
[Abstract] [Full Text]

Home page
 Genome ResHome page
C. M. Hess, J. Gasper, H. E. Hoekstra, C. E. Hill, and S. V. Edwards
MHC Class II Pseudogene and Genomic Signature of a 32-kb Cosmid in the House Finch (Carpodacus mexicanus)
Genome Res., May 1, 2000; 10(5): 613 - 623.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
A. Krasko, H. C. Schroder, S. Perovic, R. Steffen, M. Kruse, W. Reichert, I. M. Muller, and W. E. G. Muller
Ethylene Modulates Gene Expression in Cells of the Marine Sponge Suberites domuncula and Reduces the Degree of Apoptosis
J. Biol. Chem., October 29, 1999; 274(44): 31524 - 31530.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
M Kruse, R Steffen, R Batel, I. Muller, and W. Muller
Differential expression of allograft inflammatory factor 1 and of glutathione peroxidase during auto- and allograft response in marine sponges
J. Cell Sci., January 12, 1999; 112(23): 4305 - 4313.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.