Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (22)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Hyman, B. C.
Right arrow Articles by Azevedo, J. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hyman, B. C.
Right arrow Articles by Azevedo, J. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution, Vol 13, 221-232, Copyright © 1996 by Society for Molecular Biology and Evolution

ORIGINAL ARTICLE

Similar evolutionary patterning among repeated and single copy nematode mitochondrial genes

BC Hyman and JL Azevedo
Department of Biology, University of California, Riverside 92521, USA.

Ten of 12 mitochondrial protein-coding genes and the large (16S) mitochondrial rRNA gene have been identified and mapped within the Romanomermis culicivorax mitochondrial genome. This transcriptional map differs from other nematode mitochondrial DNAs (mtDNAs) with respect to gene order and transcriptional orientation of some genes. Several of these coding regions are components of a 3.0-kilobase mtDNA repeating unit, allowing a direct comparison of nucleotide and amino acid sequence composition for repeated and single copy genes. Analysis of protein-coding regions representing repeated (ND3, ND6) and single copy genes (ATPase 6, cyt.b, COI, COIII, ND1, ND4, ND5), and four repeat- associated open reading frames (ORFs) with unassigned function have revealed striking similarities in nucleotide composition, amino acid frequencies, and codon biases. Although we anticipated that reiterated protein coding regions might be evolving under relaxed selection, our results indicate that both repeated and unique mitochondrial genes appear subject to similar functional constraints.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 GeneticsHome page
S. Tang and B. C. Hyman
Mitochondrial Genome Haplotype Hypervariation Within the Isopod Parasitic Nematode Thaumamermis cosgrovei
Genetics, June 1, 2007; 176(2): 1139 - 1150.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
S.-i. Yokobori, N. Fukuda, M. Nakamura, T. Aoyama, and T. Oshima
Long-Term Conservation of Six Duplicated Structural Genes in Cephalopod Mitochondrial Genomes
Mol. Biol. Evol., November 1, 2004; 21(11): 2034 - 2046.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.