Molecular Biology and Evolution, Vol 10, 512-526, Copyright © 1993 by Society for Molecular Biology and Evolution
K Tamura and M Nei
Examining the pattern of nucleotide substitution for the control region of
mitochondrial DNA (mtDNA) in humans and chimpanzees, we developed a new
mathematical method for estimating the number of transitional and
transversional substitutions per site, as well as the total number of
nucleotide substitutions. In this method, excess transitions, unequal
nucleotide frequencies, and variation of substitution rate among different
sites are all taken into account. Application of this method to human and
chimpanzee data suggested that the transition/transversion ratio for the
entire control region was approximately 15 and nearly the same for the two
species. The 95% confidence interval of the age of the common ancestral
mtDNA was estimated to be 80,000-480,000 years in humans and 0.57-2.72 Myr
in common chimpanzees.
ORIGINAL ARTICLE
Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees
Department of Biology, Pennsylvania State University.
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M. K. Gonder, H. M. Mortensen, F. A. Reed, A. de Sousa, and S. A. Tishkoff Whole-mtDNA Genome Sequence Analysis of Ancient African Lineages Mol. Biol. Evol., March 1, 2007; 24(3): 757 - 768. [Abstract] [Full Text] [PDF] |
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I. M. Chelo, L. Ze-Ze, and R. Tenreiro Congruence of evolutionary relationships inside the Leuconostoc-Oenococcus-Weissella clade assessed by phylogenetic analysis of the 16S rRNA gene, dnaA, gyrB, rpoC and dnaK Int J Syst Evol Microbiol, February 1, 2007; 57(2): 276 - 286. [Abstract] [Full Text] [PDF] |
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R. J. P. Brown, A. W. Tarr, C. P. McClure, V. S. Juttla, N. Tagiuri, W. L. Irving, and J. K. Ball Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes J. Gen. Virol., February 1, 2007; 88(2): 458 - 469. [Abstract] [Full Text] [PDF] |
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P. J. Krug, R. A. Ellingson, R. Burton, and A. Valdes A new poecilogonous species of sea slug (Opisthobranchia: Sacoglossa) from California: comparison with the planktotrophic congener Alderia modesta (Loven, 1844) J. Mollus. Stud., February 1, 2007; 73(1): 29 - 38. [Abstract] [Full Text] [PDF] |
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S. Rosset Efficient inference on known phylogenetic trees using Poisson regression Bioinformatics, January 15, 2007; 23(2): e142 - e147. [Abstract] [Full Text] [PDF] |
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