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Molecular Biology and Evolution, Vol 10, 512-526, Copyright © 1993 by Society for Molecular Biology and Evolution


ORIGINAL ARTICLE

Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees

K Tamura and M Nei
Department of Biology, Pennsylvania State University.

Examining the pattern of nucleotide substitution for the control region of mitochondrial DNA (mtDNA) in humans and chimpanzees, we developed a new mathematical method for estimating the number of transitional and transversional substitutions per site, as well as the total number of nucleotide substitutions. In this method, excess transitions, unequal nucleotide frequencies, and variation of substitution rate among different sites are all taken into account. Application of this method to human and chimpanzee data suggested that the transition/transversion ratio for the entire control region was approximately 15 and nearly the same for the two species. The 95% confidence interval of the age of the common ancestral mtDNA was estimated to be 80,000-480,000 years in humans and 0.57-2.72 Myr in common chimpanzees.
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Evidence for Multiple Retroposition Events and Gene Evolution in the ADP/ATP Translocase Gene Family in Ranid Frogs
J. Hered., July 19, 2007; (2007) esm038v1.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
M. G. B. Blum and N. A. Rosenberg
Estimating the Number of Ancestral Lineages Using a Maximum-Likelihood Method Based on Rejection Sampling
Genetics, July 1, 2007; 176(3): 1741 - 1757.
[Abstract] [Full Text] [PDF]


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J. Virol.Home page
S. Zarate, S. L. K. Pond, P. Shapshak, and S. D. W. Frost
Comparative Study of Methods for Detecting Sequence Compartmentalization in Human Immunodeficiency Virus Type 1
J. Virol., June 15, 2007; 81(12): 6643 - 6651.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
V. Gowri-Shankar and M. Rattray
A Reversible Jump Method for Bayesian Phylogenetic Inference with a Nonhomogeneous Substitution Model
Mol. Biol. Evol., June 1, 2007; 24(6): 1286 - 1299.
[Abstract] [Full Text] [PDF]


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J. Virol.Home page
G. Pisoni, G. Bertoni, M. Puricelli, M. Maccalli, and P. Moroni
Demonstration of Coinfection with and Recombination by Caprine Arthritis-Encephalitis Virus and Maedi-Visna Virus in Naturally Infected Goats
J. Virol., May 15, 2007; 81(10): 4948 - 4955.
[Abstract] [Full Text] [PDF]


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Proc. Natl. Acad. Sci. USAHome page
K. Domes, R. A. Norton, M. Maraun, and S. Scheu
Reevolution of sexuality breaks Dollo's law
PNAS, April 24, 2007; 104(17): 7139 - 7144.
[Abstract] [Full Text] [PDF]


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J. Clin. Microbiol.Home page
G. de Souza Trindade, B. P. Drumond, M. I. M. C. Guedes, J. A. Leite, B. E. F. Mota, M. A. Campos, F. G. da Fonseca, M. L. Nogueira, Z. I. P. Lobato, C. A. Bonjardim, et al.
Zoonotic Vaccinia Virus Infection in Brazil: Clinical Description and Implications for Health Professionals
J. Clin. Microbiol., April 1, 2007; 45(4): 1370 - 1372.
[Abstract] [Full Text] [PDF]


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Syst BiolHome page
B. C. Emerson
Alarm Bells for the Molecular Clock? No Support for Ho et al.'s Model of Time-Dependent Molecular Rate Estimates
Syst Biol, April 1, 2007; 56(2): 337 - 345.
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J. Gen. Virol.Home page
T. P. Smura, N. Junttila, S. Blomqvist, H. Norder, S. Kaijalainen, A. Paananen, L. O. Magnius, T. Hovi, and M. Roivainen
Enterovirus 94, a proposed new serotype in human enterovirus species D
J. Gen. Virol., March 1, 2007; 88(3): 849 - 858.
[Abstract] [Full Text] [PDF]


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J. Gen. Virol.Home page
Y. Zhou, H. Ushijima, and T. K. Frey
Genomic analysis of diverse rubella virus genotypes
J. Gen. Virol., March 1, 2007; 88(3): 932 - 941.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
C. A. Machado, T. S. Haselkorn, and M. A. F. Noor
Evaluation of the Genomic Extent of Effects of Fixed Inversion Differences on Intraspecific Variation and Interspecific Gene Flow in Drosophila pseudoobscura and D. persimilis
Genetics, March 1, 2007; 175(3): 1289 - 1306.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
J. R. S. Meadows, I. Cemal, O. Karaca, E. Gootwine, and J. W. Kijas
Five Ovine Mitochondrial Lineages Identified From Sheep Breeds of the Near East
Genetics, March 1, 2007; 175(3): 1371 - 1379.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
M. K. Gonder, H. M. Mortensen, F. A. Reed, A. de Sousa, and S. A. Tishkoff
Whole-mtDNA Genome Sequence Analysis of Ancient African Lineages
Mol. Biol. Evol., March 1, 2007; 24(3): 757 - 768.
[Abstract] [Full Text] [PDF]


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Int. J. Syst. Evol. Microbiol.Home page
I. M. Chelo, L. Ze-Ze, and R. Tenreiro
Congruence of evolutionary relationships inside the Leuconostoc-Oenococcus-Weissella clade assessed by phylogenetic analysis of the 16S rRNA gene, dnaA, gyrB, rpoC and dnaK
Int J Syst Evol Microbiol, February 1, 2007; 57(2): 276 - 286.
[Abstract] [Full Text] [PDF]


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J. Gen. Virol.Home page
R. J. P. Brown, A. W. Tarr, C. P. McClure, V. S. Juttla, N. Tagiuri, W. L. Irving, and J. K. Ball
Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes
J. Gen. Virol., February 1, 2007; 88(2): 458 - 469.
[Abstract] [Full Text] [PDF]


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J MOLLUS STUDHome page
P. J. Krug, R. A. Ellingson, R. Burton, and A. Valdes
A new poecilogonous species of sea slug (Opisthobranchia: Sacoglossa) from California: comparison with the planktotrophic congener Alderia modesta (Loven, 1844)
J. Mollus. Stud., February 1, 2007; 73(1): 29 - 38.
[Abstract] [Full Text] [PDF]


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BioinformaticsHome page
S. Rosset
Efficient inference on known phylogenetic trees using Poisson regression
Bioinformatics, January 15, 2007; 23(2): e142 - e147.
[Abstract] [Full Text] [PDF]



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