Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (69)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Melnick, D. J.
Right arrow Articles by Ashley, M. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Melnick, D. J.
Right arrow Articles by Ashley, M. V.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Biology and Evolution, Vol 10, 282-295, Copyright © 1993 by Society for Molecular Biology and Evolution

ORIGINAL ARTICLE

mtDNA diversity in rhesus monkeys reveals overestimates of divergence time and paraphyly with neighboring species

DJ Melnick, GA Hoelzer, R Absher and MV Ashley
Department of Anthropology, Columbia University, New York, New York 10027.

Reconstructions of the human-African great ape phylogeny by using mitochondrial DNA (mtDNA) have been subject to considerable debate. One confounding factor may be the lack of data on intraspecific variation. To test this hypothesis, we examined the effect of intraspecific mtDNA diversity on the phylogenetic reconstruction of another Plio- Pleistocene radiation of higher primates, the fascicularis group of macaque (Macaca) monkey species. Fifteen endonucleases were used to identify 10 haplotypes of 40-47 restriction sites in M. mulatta, which were compared with similar data for the other members of this species group. Interpopulational, intraspecific mtDNA diversity was large (0.5%- 4.5%), and estimates of divergence time and branching order incorporating this variation were substantially different from those based on single representatives of each species. We conclude that intraspecific mtDNA diversity is substantial in at least some primate species. Consequently, without prior information on the extent of genetic diversity within a particular species, intraspecific variation must be assessed and accounted for when reconstructing primate phylogenies. Further, we question the reliability of hominoid mtDNA phylogenies, based as they are on one or a few representatives of each species, in an already depauperate superfamily of primates.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Proc R Soc BHome page
T.N.C Vidya, R. Sukumar, and D. J Melnick
Range-wide mtDNA phylogeography yields insights into the origins of Asian elephants
Proc R Soc B, March 7, 2009; 276(1658): 893 - 902.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
N. de Groot, G. G. Doxiadis, N. G. de Groot, N. Otting, C. Heijmans, A. J. M. Rouweler, and R. E. Bontrop
Genetic Makeup of the DR Region in Rhesus Macaques: Gene Content, Transcripts, and Pseudogenes
J. Immunol., May 15, 2004; 172(10): 6152 - 6157.
[Abstract] [Full Text] [PDF]

Home page
 J HeredHome page
M. K. Shimada, K. Terao, and T. Shotake
Mitochondrial Sequence Diversity Within a Subspecies of Savanna Monkeys (Cercopithecus aethiops) Is Similar to That Between Subspecies
J. Hered., January 1, 2002; 93(1): 9 - 18.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.