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Molecular Biology and Evolution, Vol 1, 29-37, Copyright © 1983 by Society for Molecular Biology and Evolution

ORIGINAL ARTICLE

Structure and evolution of human and African ape rDNA pseudogenes

E Brownell, M Krystal and N Arnheim
State University of New York, Stony Brook.

We discuss the evolutionary significance of four aberrant 18S rDNA clones that were obtained from human, chimpanzee, and gorilla DNA libraries. We show that these clones carry representatives of a small 18S rDNA pseudogene family that arose in a common ancestor of these species. Aspects of their structure and phylogenetic distribution suggest that the 18S pseudogenes no longer interact genetically with normal ribosomal genes and therefore may not be linked to nucleolus organizer regions.
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